Gerhardt Lab

Publications

Found 33 results
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2023
Madireddy A, Gerhardt J.  2023.  Visualizing DNA replication by single-molecule analysis of replicated DNA.. STAR Protoc. 4(4):102721.
2024
Xu S, Wang N, Zuccaro MV, Gerhardt J, Iyyappan R, Scatolin GNascimento, Jiang Z, Baslan T, Koren A, Egli D.  2024.  DNA replication in early mammalian embryos is patterned, predisposing lamina-associated regions to fragility.. Nat Commun. 15(1):5247.
Edwards MM, Wang N, Sagi I, Kinreich S, Benvenisty N, Gerhardt J, Egli D, Koren A.  2024.  Parent-of-origin-specific DNA replication timing is confined to large imprinted regions.. Cell Rep. 43(9):114700.
2025
McCarter K, Deshpande M, Romanski P, Stratopoulou CAnna, Zaninovic N, Tareen M, Al-Mousawi R, James D, Madireddy A, Rosenwaks Z et al..  2025.  Dysregulation of the actin cytoskeleton and FMRP causes polar body protrusion defects in human fragile X premutation and aged oocytes.. bioRxiv.
Barreto-Galvez A, Niljikar M, Gagliardi JElizabeth, Guzman CPlasencia, Zhang R, Kumar V, Juwarwala A, Pradeep A, Saxena A, Montagna C et al..  2025.  EP300 deficiency leads to chronic replication stress mediated by defective replication fork protection.. Nat Commun. 17(1):475.
Deshpande M, Gerhardt J.  2025.  Protocol to Establish Estrogen Receptor-Negative Heterozygous BRCA1 Organoids.. Methods Protoc. 8(6)
Ummarino S, Poluben L, Ebralidze AK, Autiero I, Zhang Y, Paniza T, Deshpande M, Rinaldi L, Lee JD, Bassal MA et al..  2025.  RNAs anchoring replication complex control initiation and firing of DNA replication.. Res Sq.
2026
Deshpande M, Paniza T, Brown R, Heslin K, Patel N, Madireddy A, Rosenwaks Z, Gerhardt J.  2026.  Endogenous and environmental factors that induce DNA replication defects and genomic instability in ER-negative heterozygous BRCA1 cells.. Sci Rep. 16(1)