Publications

Deshpande M, Paniza T, Jalloul N, Nanjangud G, Twarowski J, Koren A, Zaninovic N, Zhan Q, Chadalavada K, Malkova A et al..  2022.  Error-prone repair of stalled replication forks drives mutagenesis and loss of heterozygosity in haploinsufficient BRCA1 cells.. Mol Cell. 82(20):3781-3793.e7.

Deshpande M, Romanski PA, Rosenwaks Z, Gerhardt J.  2020.  Gynecological Cancers Caused by Deficient Mismatch Repair and Microsatellite Instability.. Cancers (Basel). 12(11)

Paniza T, Deshpande M, Wang N, O'Neil R, Zuccaro MV, Smith MElizabeth, Madireddy A, James D, Ecker J, Rosenwaks Z et al..  2020.  Pluripotent stem cells with low differentiation potential contain incompletely reprogrammed DNA replication.. J Cell Biol. 219(9)

Lekovich J, Man L, Xu K, Canon C, Lilienthal D, Stewart JD, Pereira N, Rosenwaks Z, Gerhardt J.  2018.  CGG repeat length and AGG interruptions as indicators of fragile X-associated diminished ovarian reserve.. Genet Med. 20(9):957-964.

Guler GD, Rosenwaks Z, Gerhardt J.  2018.  Human DNA Helicase B as a Candidate for Unwinding Secondary CGG Repeat Structures at the Gene.. Front Mol Neurosci. 11:138.

Man L, Lekovich J, Rosenwaks Z, Gerhardt J.  2017.  Fragile X-Associated Diminished Ovarian Reserve and Primary Ovarian Insufficiency from Molecular Mechanisms to Clinical Manifestations.. Front Mol Neurosci. 10:290.

Reichman D, Man L, Park L, Lis R, Gerhardt J, Rosenwaks Z, James D.  2016.  Notch hyper-activation drives trans-differentiation of hESC-derived endothelium.. Stem Cell Res. 17(2):391-400.

Gerhardt J, Bhalla AD, Butler JSergeskett, Puckett JW, Dervan PB, Rosenwaks Z, Napierala M.  2016.  Stalled DNA Replication Forks at the Endogenous GAA Repeats Drive Repeat Expansion in Friedreich's Ataxia Cells.. Cell Rep. 16(5):1218-1227.

Gerhardt J, Zaninovic N, Zhan Q, Madireddy A, Nolin SL, Ersalesi N, Yan Z, Rosenwaks Z, Schildkraut CL.  2014.  Cis-acting DNA sequence at a replication origin promotes repeat expansion to fragile X full mutation.. J Cell Biol. 206(5):599-607.

Gerhardt J, Tomishima MJ, Zaninovic N, Colak D, Yan Z, Zhan Q, Rosenwaks Z, Jaffrey SR, Schildkraut CL.  2014.  The DNA replication program is altered at the FMR1 locus in fragile X embryonic stem cells.. Mol Cell. 53(1):19-31.

Colak D, Zaninovic N, Cohen MS, Rosenwaks Z, Yang W-Y, Gerhardt J, Disney MD, Jaffrey SR.  2014.  Promoter-bound trinucleotide repeat mRNA drives epigenetic silencing in fragile X syndrome.. Science. 343(6174):1002-5.